Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cpsGPhosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. (453 aa)    
Predicted Functional Partners:
PP_1776
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 0.991
algA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).
 
 0.989
pgm
Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
  
 0.944
galU
UTP-glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
   
 0.941
rfbA
dTDP-glucose pyrophosphorylase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.933
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.924
glk
Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.
   
 
 0.923
pgi-I
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.922
pgi-II
Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme.
  
 
 0.922
tktA
Transketolase A; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.922
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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