STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpmPutative thiopurine S-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. (216 aa)    
Predicted Functional Partners:
dadA-II
D-amino-acid:quinone oxidoreductase (deaminating); Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.
    
 
 0.934
ygiD
4,5-DOPA-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
  
    0.579
PP_2013
Homologs of previously reported genes of unknown function.
   
   0.443
PP_2343
Homologs of previously reported genes of unknown function.
   
   0.443
PP_2029
Von Willebrand factor type A domain protein.
 
 
 
 0.426
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
   
 
 0.407
metH
Cobalamin-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.407
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (30%) [HD]