STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaAGlutamate-pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (403 aa)    
Predicted Functional Partners:
dadX
Alanine racemase, PLP-binding; Isomerizes L-alanine to D-alanine which is then likely oxidized to pyruvate by DadA. Shows racemase activity with both alanine stereoisomers, negligible activity with D-cysteine and L-serine, and exhibits no activity with the remaining natural chiral amino acids.
    
 0.967
ilvE
Branched-chain-amino-acid aminotransferase.
 
 
 0.922
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.916
gdhB
NAD-specific glutamate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines.
  
  
 0.913
argA
Acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase; Function experimentally demonstrated in the studied genus; enzyme.
  
 
 0.912
argJ
Glutamate N-acetyltransferase/Amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.909
gdhA
Glutamate dehydrogenase, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.908
ldh
Leucine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.908
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
   
 
 0.906
icd
Isocitrate dehydrogenase, NADP(+)-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic.
   
 0.836
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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