msrB protein (Pseudomonas putida KT2440) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_2015	msrB	PP_2015	PP_1873	Homologs of previously reported genes of unknown function.	Peptide methionine sulfoxide reductase MsrB.	0.961
alaA	gpx	PP_1872	PP_1874	Glutamate-pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	0.623
alaA	htpX	PP_1872	PP_1871	Glutamate-pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Protease HtpX; Belongs to the peptidase M48B family.	0.698
alaA	msrB	PP_1872	PP_1873	Glutamate-pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Peptide methionine sulfoxide reductase MsrB.	0.769
dctA-III	msrB	PP_2255	PP_1873	C4-dicarboxylate transport protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.	Peptide methionine sulfoxide reductase MsrB.	0.566
djlA	grpE	PP_0407	PP_4728	DnaJ-like protein DjlA.	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.539
djlA	msrA	PP_0407	PP_0336	DnaJ-like protein DjlA.	Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.477
djlA	msrB	PP_0407	PP_1873	DnaJ-like protein DjlA.	Peptide methionine sulfoxide reductase MsrB.	0.582
dsbD-I	msrA	PP_0561	PP_0336	Thiol/disulfide interchange protein 1; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.	Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.561
dsbD-I	msrB	PP_0561	PP_1873	Thiol/disulfide interchange protein 1; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.	Peptide methionine sulfoxide reductase MsrB.	0.564
gpx	alaA	PP_1874	PP_1872	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	Glutamate-pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.623
gpx	gstA	PP_1874	PP_1162	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	Protein GstA; Belongs to the GST superfamily.	0.732
gpx	htpX	PP_1874	PP_1871	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	Protease HtpX; Belongs to the peptidase M48B family.	0.505
gpx	msrA	PP_1874	PP_0336	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.445
gpx	msrB	PP_1874	PP_1873	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	Peptide methionine sulfoxide reductase MsrB.	0.887
grpE	djlA	PP_4728	PP_0407	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	DnaJ-like protein DjlA.	0.539
grpE	htpX	PP_4728	PP_1871	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	Protease HtpX; Belongs to the peptidase M48B family.	0.851
grpE	msrB	PP_4728	PP_1873	Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	Peptide methionine sulfoxide reductase MsrB.	0.701
gstA	gpx	PP_1162	PP_1874	Protein GstA; Belongs to the GST superfamily.	Hydroperoxy fatty acid reductase gpx1; Belongs to the glutathione peroxidase family.	0.732
gstA	msrA	PP_1162	PP_0336	Protein GstA; Belongs to the GST superfamily.	Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.444