STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1968TetR family transcriptional regulator. (211 aa)    
Predicted Functional Partners:
PP_1969
Putative Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
       0.519
PP_1970
Putative Lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.488
PP_1971
Homologs of previously reported genes of unknown function.
       0.488
PP_2597
Homologs of previously reported genes of unknown function; Unknown function.
  
    0.477
PP_5077
Homologs of previously reported genes of unknown function.
  
   
 0.472
ycfH
tRNA D-aminoacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biologicalprocesses : Maintain.
  
    0.467
ycgR
Flagellar brake protein YcgR; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity). Binds c-di-GMP with a dissociation constant of 165 nM. Binds 2 intercalated (c-di-GMP) dimers per subunit.
  
     0.458
PP_5121
Homologs of previously reported genes of unknown function.
  
     0.453
holB
DNA polymerase III subunit delta'.
       0.443
PP_4176
Putative 5-oxo-L-prolinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.427
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.