STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2038long-chain-fatty-acid--CoA ligase; Function of strongly homologous gene; enzyme; Fatty acid and phospholipid metabolism. (515 aa)    
Predicted Functional Partners:
PP_2039
Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.755
PP_2563
Putative Antibiotic biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
0.676
fabD
malonyl-CoA-ACP transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
    
 0.613
PP_2040
Major facilitator family transporter.
  
    0.562
PP_1700
Acyltransferase.
  
 
 0.558
pvdD
Non-ribosomal peptide synthetase; Function experimentally demonstrated in the studied genus; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
 
 
0.558
PP_2213
Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.551
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.533
PP_1955
Cytochrome P450 family protein.
 
 0.511
fadB
enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
 0.509
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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