Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_2055Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. (359 aa)    
Predicted Functional Partners:
gllC
4-carboxy-4-hydroxy-2-oxoadipic acid aldolase; Catalyzes the conversion of 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA) to pyruvate and oxaloacetate, the last step of gallate degradation pathway; Belongs to the LigK/PcmE family.
 
    0.775
gllB
4-oxalmesaconate hydratase; Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA). Mediates the third step of gallate degradation pathway.
 
     0.758
ybhD
Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Transcription; Belongs to the LysR transcriptional regulatory family.
 
     0.712
dctA-II
C4-dicarboxylate transport protein; Function of strongly homologous gene; transporter; Energy metabolism; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
    0.651
acnA-II
Aconitate hydratase 1; Function of strongly homologous gene; enzyme; Energymetabolism : Anaerobic.
 
  
 0.635
glllA
Gallate dioxygenase; Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Mediates the first step of gallate degradation pathway.
 
    0.593
PP_1699
2-pyrone-4,6-dicarboxylic acid hydrolase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
   
 0.572
acnA-I
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
  
 0.557
PP_4462
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.545
PP_1389
Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
 
  
 0.535
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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