STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2064Multidrug efflux RND membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (365 aa)    
Predicted Functional Partners:
PP_2065
Multidrug efflux RND transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.968
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.868
PP_0906
Putative Multidrug efflux RND transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.862
mexF
Multidrug efflux RND transporter MexF.
 
 
 0.707
mdtC
Multidrug efflux transport system - membrane subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.705
mdtB
Multidrug efflux transport system - membrane subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.638
PP_5174
Efflux membrane fusion protein, RND family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
    0.630
mexD
Multidrug efflux RND transporter MexD.
 
 
 0.605
mexB
Multidrug resistance protein MexB.
 
 
 0.579
ttgB
Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.537
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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