STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2129Homologs of previously reported genes of unknown function. (267 aa)    
Predicted Functional Partners:
gbcB
Putative glycine-betaine dioxygenase subunit; Function experimentally demonstrated in the studied genus; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation.
     0.918
paaE
Ring 1,2-phenylacetyl-CoA epoxidase, reductase subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
      0.903
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
      0.858
vanB
Vanillate O-demethylase oxidoreductase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism).
      0.791
PP_1957
Oxidoreductase, Pdr/VanB family.
      0.717
PP_1163
Oxidoreductase, FAD-binding.
      0.676
PP_2128
Putative CheV-like chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
    0.667
pdxH
Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
 
      0.602
pydA
NADP-dependent dihydropyrimidine dehydrogenase subunit PreA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
 
    0.598
PP_2838
Conserved protein of unknown function; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
  
     0.454
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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