Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_2177Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (184 aa)    
Predicted Functional Partners:
PP_3125
Putative transcriptional regulator (Cro/CI family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.822
PP_2245
Transcriptional regulator, Cro/CI family.
  
  
 0.743
puuA-I
Glutamate-putrescine ligase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the glutamine synthetase family.
  
  
 0.723
spuA
Glutamine amidotransferase; Function experimentally demonstrated in the studied genus; enzyme; Purines, pyrimidines, nucleosides, and nucleotides.
  
  
 0.656
PP_2176
Transcriptional regulator, LysR family; Function of strongly homologous gene; regulator; Regulatory functions; Belongs to the LysR transcriptional regulatory family.
  
  
 0.524
puuR
DNA-binding transcriptional repressor PuuR-putrescine; Function of homologous gene experimentally demonstrated in an other organism; regulator; Regulatory functions.
 
 
0.477
pheA
Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme.
  
  
 0.468
PP_0727
Homologs of previously reported genes of unknown function.
 
  
 0.466
PP_2175
Putative 3-oxoacyl-(Acyl-carrier-protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.456
cobB-2
Deacetylase of acetyl-CoA synthetase, NAD-dependent; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
  
    0.452
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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