Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_2187Universal stress protein family. (287 aa)    
Predicted Functional Partners:
PP_3288
Universal stress protein family.
  
    0.778
PP_3290
Universal stress protein family.
  
     0.774
PP_2662
Homologs of previously reported genes of unknown function.
  
     0.653
PP_2132
Universal stress protein.
   
  
 0.637
oprG
Outer membrane protein OprG.
 
  
 0.580
PP_0973
Nucleoid-associated protein PP_0973.
  
     0.577
PP_2188
Putative tRNA-(Ms(2)io(6)a)-hydroxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.562
sdhE
Conserved protein of unknown function, DUF339 family; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...]
  
     0.538
PP_2099
Homologs of previously reported genes of unknown function.
  
     0.512
PP_5077
Homologs of previously reported genes of unknown function.
 
    0.511
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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