node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PP_0097 | PP_2015 | PP_0097 | PP_2015 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.748 |
PP_0097 | PP_2166 | PP_0097 | PP_2166 | Homologs of previously reported genes of unknown function. | Anti-anti-sigma factor. | 0.694 |
PP_0097 | PP_2188 | PP_0097 | PP_2188 | Homologs of previously reported genes of unknown function. | Putative tRNA-(Ms(2)io(6)a)-hydroxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.503 |
PP_0097 | nfuA | PP_0097 | PP_2378 | Homologs of previously reported genes of unknown function. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.508 |
PP_0097 | sdhD | PP_0097 | PP_4192 | Homologs of previously reported genes of unknown function. | Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.706 |
PP_0097 | sdhE | PP_0097 | PP_1424 | Homologs of previously reported genes of unknown function. | Conserved protein of unknown function, DUF339 family; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.702 |
PP_2015 | PP_0097 | PP_2015 | PP_0097 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.748 |
PP_2015 | PP_2166 | PP_2015 | PP_2166 | Homologs of previously reported genes of unknown function. | Anti-anti-sigma factor. | 0.754 |
PP_2015 | PP_2188 | PP_2015 | PP_2188 | Homologs of previously reported genes of unknown function. | Putative tRNA-(Ms(2)io(6)a)-hydroxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.718 |
PP_2015 | nfuA | PP_2015 | PP_2378 | Homologs of previously reported genes of unknown function. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.746 |
PP_2015 | sdhC | PP_2015 | PP_4193 | Homologs of previously reported genes of unknown function. | Succinate dehydrogenase membrane b-556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. | 0.466 |
PP_2015 | sdhD | PP_2015 | PP_4192 | Homologs of previously reported genes of unknown function. | Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.791 |
PP_2015 | sdhE | PP_2015 | PP_1424 | Homologs of previously reported genes of unknown function. | Conserved protein of unknown function, DUF339 family; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.532 |
PP_2015 | topA | PP_2015 | PP_2139 | Homologs of previously reported genes of unknown function. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.708 |
PP_2166 | PP_0097 | PP_2166 | PP_0097 | Anti-anti-sigma factor. | Homologs of previously reported genes of unknown function. | 0.694 |
PP_2166 | PP_2015 | PP_2166 | PP_2015 | Anti-anti-sigma factor. | Homologs of previously reported genes of unknown function. | 0.754 |
PP_2166 | PP_2188 | PP_2166 | PP_2188 | Anti-anti-sigma factor. | Putative tRNA-(Ms(2)io(6)a)-hydroxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.535 |
PP_2166 | nfuA | PP_2166 | PP_2378 | Anti-anti-sigma factor. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.530 |
PP_2166 | sdhD | PP_2166 | PP_4192 | Anti-anti-sigma factor. | Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.546 |
PP_2166 | sdhE | PP_2166 | PP_1424 | Anti-anti-sigma factor. | Conserved protein of unknown function, DUF339 family; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...] | 0.471 |