STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2238Putative metallopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides. (633 aa)    
Predicted Functional Partners:
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
  
 0.902
amaC
D-lysine aminotransferase; Function experimentally demonstrated in the studied strain; enzyme; Aminoacidbiosynthesis : Aromatic amino acid family.
    
 
 0.766
creA
Creatinase; Function experimentally demonstrated in the studied species; enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides.
      
 0.741
ppx
Exopolyphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Phosphorus compounds; Belongs to the GppA/Ppx family.
      
 0.732
pip
Proline iminopeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S33 family.
   
 
 0.676
PP_2236
Putative hydrolase of the alpha/beta superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.541
PP_2237
Homologs of previously reported genes of unknown function.
       0.534
tyrB
Aromatic-amino-acid aminotransferase; Function experimentally demonstrated in the studied strain; enzyme; Aminoacidbiosynthesis : Aspartate family.
   
 
 0.486
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
      0.468
amiD
1,6-anhydro-N-acetylmuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.439
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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