STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2266DNA-directed RNA polymerase, bacteriophage and mitochondrial type. (852 aa)    
Predicted Functional Partners:
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 0.975
PP_2297
Putative integrative genetic element Ppu40, integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Mobileandextrachromosomalelementfunctions : Transposon functions; Belongs to the 'phage' integrase family.
   
  
 0.930
PP_1532
Putative Phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.
      
 0.840
PP_2270
Putative DNA primase/helicase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
  
    0.769
PP_2279
Head-to-tail joining protein.
  
    0.759
PP_2293
DNA maturase B.
  
    0.750
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.741
PP_2273
DNA polymerase I from phage origin; Function of strongly homologous gene; extrachromosomal origin; DNAmetabolism : DNA replication, recombination, and repair.
  
  
 0.709
PP_2276
Putative phage exonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Mobileandextrachromosomalelementfunctions : Prophage functions.
  
  
 0.597
acnA-I
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.526
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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