| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_2304 | clpX | PP_2304 | PP_2301 | Putative Peptidyl-prolyl cis-trans isomerase D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.774 |
| PP_2304 | hupB | PP_2304 | PP_2303 | Putative Peptidyl-prolyl cis-trans isomerase D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.920 |
| PP_2304 | lon-II | PP_2304 | PP_2302 | Putative Peptidyl-prolyl cis-trans isomerase D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.841 |
| PP_3693 | hupB | PP_3693 | PP_2303 | Putative Transcriptional regulator MvaT, P16 subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.659 |
| PP_3765 | hupB | PP_3765 | PP_2303 | H-NS family protein MvaT. | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.696 |
| clpX | PP_2304 | PP_2301 | PP_2304 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Putative Peptidyl-prolyl cis-trans isomerase D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.774 |
| clpX | hupB | PP_2301 | PP_2303 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.709 |
| clpX | ihfA | PP_2301 | PP_2471 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.756 |
| clpX | lon-II | PP_2301 | PP_2302 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.939 |
| hupB | PP_2304 | PP_2303 | PP_2304 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Putative Peptidyl-prolyl cis-trans isomerase D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.920 |
| hupB | PP_3693 | PP_2303 | PP_3693 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Putative Transcriptional regulator MvaT, P16 subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.659 |
| hupB | PP_3765 | PP_2303 | PP_3765 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | H-NS family protein MvaT. | 0.696 |
| hupB | clpX | PP_2303 | PP_2301 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.709 |
| hupB | ihfA | PP_2303 | PP_2471 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.609 |
| hupB | lon-II | PP_2303 | PP_2302 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.786 |
| hupB | pheA | PP_2303 | PP_1769 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme. | 0.509 |
| hupB | rplR | PP_2303 | PP_0470 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.831 |
| hupB | rplW | PP_2303 | PP_0456 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.567 |
| hupB | rpsO | PP_2303 | PP_4709 | DNA binding regulator, beta subunit B; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.550 |
| ihfA | clpX | PP_2471 | PP_2301 | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.756 |