Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_2320Homologs of previously reported genes of unknown function. (325 aa)    
Predicted Functional Partners:
PP_1451
Homologs of previously reported genes of unknown function.
 
  
 0.802
PP_2319
Homologs of previously reported genes of unknown function.
       0.737
tesA
acyl-CoA thioesterase I/protease I/lysophospholipase L1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
     
 0.729
ybbA
Putative ABC transporter - ATP binding subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
  
    0.677
PP_2316
Putative ABC transporter, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.660
ftsI
Peptidoglycan DD transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
  
 0.598
dacA
D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family.
    
 0.567
PP_1058
Homologs of previously reported genes of unknown function.
      
 0.543
greB
Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.
       0.488
ybgF
Periplasmic subunit of the TolQRA transport system; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
  
  
 0.445
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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