Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_23252-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa)    
Predicted Functional Partners:
PP_2998
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
 
 
0.932
panE
Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
 
0.929
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.920
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.918
PP_2326
Universal stress protein.
 
   
 0.644
aroF-I
Tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
  
    0.612
alkB
Alpha-ketoglutarate- and Fe(II)-dependent dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : Restriction/modification.
   
    0.490
cysB
Transcriptional dual regulator / CysB-O-acetyl-L-serine; Function of homologous gene experimentally demonstrated in an other organism; regulator; Aminoacidbiosynthesis : Serine family; Belongs to the LysR transcriptional regulatory family.
       0.458
fucD
L-fuconate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Pentose phosphate pathway; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
   
    0.419
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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