STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (244 aa)    
Predicted Functional Partners:
cysNC
Sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 0.999
cysI
Sulphite reductase hemoprotein, beta subunit.
 
 0.999
cysD
Sulfate adenylyltransferase subunit 2.
  
 0.997
cysA
Sulfate/thiosulfate import ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
  
 0.973
cysG
Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.971
PP_0860
Putative Sulfite reductase, flavoprotein component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.968
PP_1703
Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 
 0.967
cysQ
Adenosine-3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
  
 
 0.939
ssuE
NAD(P)H-dependent FMN reductase subunit; Probably forms a two-component reduced flavin mononucleotide- dependent monooxygenase by binding to SsuD. Required for growth on aliphatic sulfonates or methionine but not arylsulfonates (By similarity); Belongs to the SsuE family.
   
 
 0.922
msuE
FMN reductase (NADPH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Sulfur metabolism.
   
 
 0.922
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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