STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpFAconitate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (396 aa)    
Predicted Functional Partners:
acnA-II
Aconitate hydratase 1; Function of strongly homologous gene; enzyme; Energymetabolism : Anaerobic.
 
 
 0.998
prpD
2-methylcitrate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
  
 
  0.972
acnB
Bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the aconitase/IPM isomerase family.
  
 
 0.948
mmgF
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.940
prpC
Methylcitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the citrate synthase family.
 
  
 0.912
prpE
propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
  
  
 0.766
dapF-2
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
   
  
 0.764
acnA-I
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
  
 0.761
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
      
 0.757
citN
Citrate transporter.
     
 0.714
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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