Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PP_2349CBS domain protein. (384 aa)    
Predicted Functional Partners:
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.690
PP_4764
Histone deacetylase family protein.
  
  
 0.486
aphA
Acetylpolyamine aminohydrolase.
  
  
 0.486
PP_3243
Acetyltransferase, GNAT family.
  
    0.420
PP_2345
Homologs of previously reported genes of unknown function.
       0.412
PP_2346
Homologs of previously reported genes of unknown function.
       0.412
PP_4684
Conserved protein of unknown function with kinase-like domain; Homologs of previously reported genes of unknown function; Unknown function.
       0.412
PP_2347
DNA-binding response regulator.
       0.411
PP_2348
Sensor histidine kinase.
       0.411
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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