STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctiEsterified fatty acid cis/trans isomerase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis. (766 aa)    
Predicted Functional Partners:
metH
Cobalamin-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
    0.605
algX
Alginate biosynthesis protein AlgX; Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. Probably has acetyltransferase activity in vivo (By similarity).
  
     0.594
PP_1747
Conserved protein of unknown function, UPF0270 family; Homologs of previously reported genes of unknown function; Unknown function; Belongs to the UPF0270 family.
  
     0.549
PP_2377
Putative acetyltransferase Act; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
       0.530
PP_0330
Hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.503
PP_2374
Homologs of previously reported genes of unknown function.
 
    0.479
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
    0.461
algJ
Probable alginate O-acetylase AlgJ; Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity).
  
     0.458
PP_0143
Homologs of previously reported genes of unknown function.
  
     0.429
alg8
Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid.
  
     0.414
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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