Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lpxOAFe(2+)/alpha-ketoglutarate-dependent dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cell envelope. (299 aa)    
Predicted Functional Partners:
PP_0024
Putative membrane-associated metal-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.905
PP_4570
Homologs of previously reported genes of unknown function.
  
  
 
0.905
PP_4592
Putative metal dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
     
 0.905
PP_1924
Putative Phosphinothricin N-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.868
imm
Colicin-E7 immunity protein.
      
 0.858
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
      
 0.750
mnmA
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
      
 0.706
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
   
  
 0.695
PP_4920
Putative Lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.610
atsK
Alpha-ketoglutarate-dependent sulfonate dioxygenase; Catalyzes the alpha-ketoglutarate-dependent hydroxylation of taurine yielding sulfite and aminoacetaldehyde after decomposition of an unstable intermediate.
  
   
 0.595
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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