STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfnB6,7-dihydropteridine reductase; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Degradation. (217 aa)    
Predicted Functional Partners:
PP_2486
NADH-dependent flavin oxidoreductase, Oye family.
  
 
 0.903
nemA
N-ethylmaleimide reductase, FMN-linked; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
  
 
 0.903
mdaB
Modulator of drug activity B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport.
 
  
 0.867
PP_3720
Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.847
ecd
Flavoprotein; Belongs to the flavin oxidoreductase frp family.
      
 0.730
azoR2
FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.
      
 0.689
ybgI
Putative metal-binding hydrolase-oxidase enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknown function.
     
 0.682
PP_2431
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
     0.639
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.565
ycaO
Cofactor of beta-methylthiolation of ribosomal protein S12; Function of homologous gene experimentally demonstrated in an other organism; factor; Unknown function.
  
  
 0.554
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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