STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xreConserved protein of unknown function; Probable antitoxin component of a type II toxin-antitoxin (TA) system. In vivo probably neutralizes the toxic effect of cognate toxin Res. (159 aa)    
Predicted Functional Partners:
res
Conserved protein of unknown function; Toxic component of a type II toxin-antitoxin (TA) system. Expression in E.coli inhibits cell growth. In vivo it is probably neutralized by cognate antitoxin Xre; this has not been shown upon expression in E.coli. Probably depletes intracellular NAD(+) (By similarity); Belongs to the MbcT/ParT/Res family.
 
 
 0.999
mqsA
Antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Regulatory functions.
      
 0.818
PP_1480
Homologs of previously reported genes of unknown function.
      
 0.815
PP_4151
Excisionase domain protein.
  
   
 0.787
PP_2870
Putative spermidine/putrescine-binding periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Biologicalprocesses : Circulate.
      
 0.766
hicB
HicB protein.
   
  
 0.743
PP_2036
Putative 4-hydroxy-tetrahydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Aminoacidbiosynthesis : Aspartate family; Belongs to the DapA family.
      
 0.742
PP_4362
Homologs of previously reported genes of unknown function.
      
 0.742
yggW
Coproporphyrinogen/heterocyclic compound oxidase (aerobic); Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
      
 0.708
PP_1268
Putative HtrA suppressor protein sohA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  
 0.658
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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