Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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[Homology]
Score
NuhRibonucleoside hydrolase; Function experimentally demonstrated in the studied strain; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions; Belongs to the IUNH family. (322 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.994
rbsD
Ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
  
  
 0.968
codA
Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions.
 
 
 0.801
rbsC
D-ribose ABC transporter - permease subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism; Belongs to the binding-protein-dependent transport system permease family.
  
    0.745
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.696
gcvH-II
Glycine cleavage system H protein 2; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
  
 0.695
rbsR
DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions.
 
   
 0.684
rbsB
Ribose ABC transporter, periplasmic ribose-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.651
gcvT-II
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
      
 0.651
polA
DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.624
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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