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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
PP_2504Putative tautomerase K2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 4-oxalocrotonate tautomerase family. (69 aa)    
Predicted Functional Partners:
PP_2503
Putative 3-oxoacyl-(Acyl-carrier-protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.839
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
  
   
 0.816
PP_2037
Putative Aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.812
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
      
 0.811
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
     
 0.785
PP_5530
Protein of unknown function; No homology to any previously reported sequences.
       0.773
fucD
L-fuconate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Pentose phosphate pathway; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
      
 0.567
benD
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.537
PP_5531
Homologs of previously reported genes of unknown function; Unknown function.
       0.481
ribF
Bifunctional riboflavin kinase / FMN adenylyltransferaseFMN adenylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Riboflavin, FMN, and FAD; Belongs to the ribF family.
   
 
 0.431
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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