Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_2505GAF domain/GGDEF domain protein. (345 aa)    
Predicted Functional Partners:
PP_0914
GGDEF domain protein.
 
 0.986
PP_3672
Homologs of previously reported genes of unknown function.
  
 0.981
PP_3728
Sensor histidine kinase/response regulator.
  
 0.971
gacS
Sensor protein GacS.
  
 0.969
PP_2557
Sensory box protein.
 
 
0.946
PP_0131
Putative membrane-anchored phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.944
PP_4173
Sensor histidine kinase/response regulator.
  
 0.944
PP_1875
Sensor histidine kinase/response regulator.
  
 0.941
PP_3758
Response regulator/sensor histidine kinase.
 
  
 0.939
PP_0218
Sensory box protein.
 
0.935
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.