Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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gllC4-carboxy-4-hydroxy-2-oxoadipic acid aldolase; Catalyzes the conversion of 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA) to pyruvate and oxaloacetate, the last step of gallate degradation pathway; Belongs to the LigK/PcmE family. (238 aa)    
Predicted Functional Partners:
gllB
4-oxalmesaconate hydratase; Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA). Mediates the third step of gallate degradation pathway.
 
 0.999
gllD
4-oxalomesaconate tautomerase; Catalyzes the tautomerization of the 4-oxalomesaconic acid keto (OMAketo) generated by GalA dioxygenase to 4-oxalomesaconic acid enol (OMAenol). Mediates the second step in gallate degradation pathway.
 
   
 0.994
gllR
HTH-type transcriptional regulator GalR; Transcriptional regulator for the galBCD and galTAP operons, encoding genes of the gallate degradation pathway.
 
   
 0.976
glllA
Gallate dioxygenase; Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Mediates the first step of gallate degradation pathway.
 
  
 0.964
PP_1157
Acetolactate synthase; Belongs to the TPP enzyme family.
     
  0.900
PP_1394
Putative Acetolactate synthase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the TPP enzyme family.
     
  0.900
ilvH
Acetohydroxybutanoate synthase / acetolactate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Pyruvate family.
     
  0.900
ilvI
Acetohydroxybutanoate synthase / acetolactate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Pyruvate family.
     
  0.900
PP_2084
Putative regulator of ribonuclease activity; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
  
   
 0.860
ligC
Putative 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
   
 0.857
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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