Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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gllB4-oxalmesaconate hydratase; Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA). Mediates the third step of gallate degradation pathway. (258 aa)    
Predicted Functional Partners:
gllD
4-oxalomesaconate tautomerase; Catalyzes the tautomerization of the 4-oxalomesaconic acid keto (OMAketo) generated by GalA dioxygenase to 4-oxalomesaconic acid enol (OMAenol). Mediates the second step in gallate degradation pathway.
 
  
 0.999
gllC
4-carboxy-4-hydroxy-2-oxoadipic acid aldolase; Catalyzes the conversion of 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA) to pyruvate and oxaloacetate, the last step of gallate degradation pathway; Belongs to the LigK/PcmE family.
 
 0.999
gllR
HTH-type transcriptional regulator GalR; Transcriptional regulator for the galBCD and galTAP operons, encoding genes of the gallate degradation pathway.
 
  
 0.977
glllA
Gallate dioxygenase; Ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate. Mediates the first step of gallate degradation pathway.
 
  
 0.945
ligC
Putative 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
  
 0.827
PP_3822
Cytochrome c family protein.
      
 0.767
PP_2055
Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
 
     0.758
gllP
Porin-like protein; Probable transporter, possibly involved in the gallate degradation pathway. May play a role in the uptake of low gallate concentrations that may exist in the natural habitats of P.putida (Probable).
      
 0.749
PP_4462
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.702
PP_1699
2-pyrone-4,6-dicarboxylic acid hydrolase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
     0.668
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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