| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0747 | PP_2531 | PP_0747 | PP_2531 | Hypoxanthine-guanine phosphoribosyltransferase. | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.900 |
| PP_0747 | guaA | PP_0747 | PP_1032 | Hypoxanthine-guanine phosphoribosyltransferase. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.971 |
| PP_0747 | guaB | PP_0747 | PP_1031 | Hypoxanthine-guanine phosphoribosyltransferase. | IMP dehydrogenase and single strand DNA binding factor; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.965 |
| PP_0747 | upp | PP_0747 | PP_0746 | Hypoxanthine-guanine phosphoribosyltransferase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.842 |
| PP_0747 | yfiH | PP_0747 | PP_0624 | Hypoxanthine-guanine phosphoribosyltransferase. | Uncharacterized protein YfiH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.924 |
| PP_0747 | yrfG | PP_0747 | PP_0259 | Hypoxanthine-guanine phosphoribosyltransferase. | Purine nucleotidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.901 |
| PP_2531 | PP_0747 | PP_2531 | PP_0747 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.900 |
| PP_2531 | guaA | PP_2531 | PP_1032 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.900 |
| PP_2531 | guaB | PP_2531 | PP_1031 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | IMP dehydrogenase and single strand DNA binding factor; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.900 |
| PP_2531 | maf | PP_2531 | PP_0936 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.900 |
| PP_2531 | nadC | PP_2531 | PP_0787 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Quinolinate phosphoribosyltransferase (decarboxylating) monomer; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Pyridine nucleotides; Belongs to the NadC/ModD family. | 0.900 |
| PP_2531 | nudC | PP_2531 | PP_4029 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | NADH pyrophosphatase. | 0.918 |
| PP_2531 | pde | PP_2531 | PP_4917 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.902 |
| PP_2531 | upp | PP_2531 | PP_0746 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| PP_2531 | yfiH | PP_2531 | PP_0624 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Uncharacterized protein YfiH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Unknown function; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.916 |
| PP_2531 | yrfG | PP_2531 | PP_0259 | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Purine nucleotidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
| guaA | PP_0747 | PP_1032 | PP_0747 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.971 |
| guaA | PP_2531 | PP_1032 | PP_2531 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative 5-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.900 |
| guaA | guaB | PP_1032 | PP_1031 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase and single strand DNA binding factor; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | upp | PP_1032 | PP_0746 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.663 |