| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_2550 | efp | PP_2550 | PP_1858 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.623 |
| PP_2550 | lepA | PP_2550 | PP_1431 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.668 |
| PP_2550 | rplL | PP_2550 | PP_0446 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.729 |
| PP_2550 | rplM | PP_2550 | PP_1315 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.671 |
| PP_2550 | rplQ | PP_2550 | PP_0480 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L17. | 0.632 |
| PP_2550 | rplS | PP_2550 | PP_1465 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.729 |
| PP_2550 | rplT | PP_2550 | PP_2468 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.623 |
| PP_2550 | rpmA | PP_2550 | PP_0689 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.659 |
| PP_2550 | rpmF | PP_2550 | PP_1911 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.624 |
| PP_2550 | rpsP | PP_2550 | PP_1462 | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.770 |
| efp | PP_2550 | PP_1858 | PP_2550 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. | 0.623 |
| efp | lepA | PP_1858 | PP_1431 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.761 |
| efp | rplL | PP_1858 | PP_0446 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.596 |
| efp | rplM | PP_1858 | PP_1315 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.977 |
| efp | rplQ | PP_1858 | PP_0480 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L17. | 0.901 |
| efp | rplS | PP_1858 | PP_1465 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.962 |
| efp | rplT | PP_1858 | PP_2468 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.941 |
| efp | rpmA | PP_1858 | PP_0689 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.951 |
| efp | rpmF | PP_1858 | PP_1911 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.974 |
| efp | rpsP | PP_1858 | PP_1462 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.952 |