Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_2558Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (452 aa)    
Predicted Functional Partners:
hasE
Metalloprotease secretion protein.
 
 0.989
aprDA
Alkaline protease secretion transporter ATP-binding protein; Function experimentally demonstrated in the studied genus; transporter.
 
  
 0.967
PP_2064
Multidrug efflux RND membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.931
PP_2555
Homologs of previously reported genes of unknown function.
  
  
 0.890
PP_2561
Putative secreted hemolysin-type calcium-binding bacteriocin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Cellularprocesses : Toxin production and resistance.
 
  
 0.873
PP_2557
Sensory box protein.
     
 0.853
pvdR
ABC export system, membrane fusion protein; Function of strongly homologous gene; transporter; Transport and binding proteins; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.849
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.841
PP_3455
Multidrug efflux RND membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.835
PP_2562
Homologs of previously reported genes of unknown function.
   
  
 0.818
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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