STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2588Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)    
Predicted Functional Partners:
PP_2587
LuxR family transcriptional regulator.
 
    0.711
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
 0.613
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
  
 0.607
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.495
PP_4020
Putative Oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.490
PP_3146
Putative Oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.452
PP_2589
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
 
    0.451
spuB
Glutamylpolyamine synthetase; Function experimentally demonstrated in the studied genus; enzyme; Centralintermediarymetabolism : Polyamine biosynthesis; Belongs to the glutamine synthetase family.
    0.451
PP_2552
DOPA decarboxylase.
    
 0.448
PP_5273
Putative Oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.443
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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