| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_2587 | PP_2588 | PP_2587 | PP_2588 | LuxR family transcriptional regulator. | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.709 |
| PP_2588 | PP_2587 | PP_2588 | PP_2587 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | LuxR family transcriptional regulator. | 0.709 |
| PP_2588 | bioB | PP_2588 | PP_0362 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.560 |
| PP_2588 | bioD | PP_2588 | PP_0366 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.605 |
| PP_2588 | bioF | PP_2588 | PP_0363 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.507 |
| PP_2588 | kauB | PP_2588 | PP_5278 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-guanidinobutyraldehyde dehydrogenase; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family. | 0.902 |
| PP_2588 | patD | PP_2588 | PP_1481 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Medium chain aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family. | 0.902 |
| PP_2588 | prr | PP_2588 | PP_2801 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Gamma-aminobutyraldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family. | 0.902 |
| PP_2588 | speB | PP_2588 | PP_2196 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Agmatinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Polyamine biosynthesis; Belongs to the arginase family. | 0.931 |
| PP_2588 | speC | PP_2588 | PP_0864 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Ornithine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.903 |
| PP_2588 | spuC-II | PP_2588 | PP_5182 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Polyamine:pyruvate transaminase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.907 |
| bioB | PP_2588 | PP_0362 | PP_2588 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.560 |
| bioB | bioD | PP_0362 | PP_0366 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioB | bioF | PP_0362 | PP_0363 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.998 |
| bioB | spuC-II | PP_0362 | PP_5182 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Polyamine:pyruvate transaminase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.836 |
| bioD | PP_2588 | PP_0366 | PP_2588 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.605 |
| bioD | bioB | PP_0366 | PP_0362 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.999 |
| bioD | bioF | PP_0366 | PP_0363 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.999 |
| bioD | spuC-II | PP_0366 | PP_5182 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Polyamine:pyruvate transaminase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.650 |
| bioF | PP_2588 | PP_0363 | PP_2588 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.507 |