STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligCPutative 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biologicalprocesses : Scavenge (Catabolism). (350 aa)    
Predicted Functional Partners:
PP_2603
Homologs of previously reported genes of unknown function.
 
  
 0.970
quiC
Putative 3-dehydroshikimate dehydratase; Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
 
  
 0.917
gllC
4-carboxy-4-hydroxy-2-oxoadipic acid aldolase; Catalyzes the conversion of 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA) to pyruvate and oxaloacetate, the last step of gallate degradation pathway; Belongs to the LigK/PcmE family.
 
  
 0.904
gllB
4-oxalmesaconate hydratase; Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA). Mediates the third step of gallate degradation pathway.
 
  
 0.879
gllD
4-oxalomesaconate tautomerase; Catalyzes the tautomerization of the 4-oxalomesaconic acid keto (OMAketo) generated by GalA dioxygenase to 4-oxalomesaconic acid enol (OMAenol). Mediates the second step in gallate degradation pathway.
 
   
 0.875
ligB
DNA ligase B; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
   
  
 0.849
lysS
Lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.764
rffG
dTDP-glucose 4,6-dehydratase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.757
kguE
Putative epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energy metabolism.
  
  
 0.757
PP_0550
Homologs of previously reported genes of unknown function.
   
 
 0.749
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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