STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_2603Homologs of previously reported genes of unknown function. (271 aa)    
Predicted Functional Partners:
quiC
Putative 3-dehydroshikimate dehydratase; Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
   
 0.975
ligC
Putative 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biologicalprocesses : Scavenge (Catabolism).
 
  
 0.952
PP_2601
Transcriptional regulator, IclR family.
 
    0.866
PP_2600
Homologs of previously reported genes of unknown function.
 
     0.845
PP_2605
Homologs of previously reported genes of unknown function.
 
     0.782
PP_2607
Homologs of previously reported genes of unknown function.
 
    0.763
aroE-2
Putative quinate/shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.614
PP_5367
Transketolase domain protein.
 
     0.475
PP_2608
Shikimate dehydrogenase family protein.
  
 0.460
udh
Uronate dehydrogenase; Catalyzes the oxidation of beta-D-galacturonate and beta-D- glucuronate to galactarate and D-glucarate, respectively. Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
   
 0.404
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.