Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PP_2646Homologs of previously reported genes of unknown function. (131 aa)    
Predicted Functional Partners:
mgtA
Magnesium transporter, ATP-dependent; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energymetabolism : ATP-proton motive force interconversion.
  
    0.795
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
      
 0.767
PP_2695
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
      
 0.765
yciH
Translation-related factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Unknown function.
      
 0.762
frmC
S-formylglutathione hydrolase / S-lactoylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
      
 0.707
arcB
Ornithine carbamoyltransferase, catabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
      
 0.700
gshA
Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
      
 0.637
frmA
Formaldehyde dehydrogenase, glutathione-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Fermentation.
   
  
 0.566
xenB
Xenobiotic reductase B.
      
 0.549
calA
Coniferyl alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
      
 0.523
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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