Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_2671Sensor histidine kinase. (424 aa)    
Predicted Functional Partners:
exaE
Transcriptional activator protein ExaE.
 
 
 0.999
uhpA
DNA-binding response regulator UhpA.
 
 0.985
agmR
Glycerol metabolism activator.
 
 
 0.886
PP_2675
Cytochrome c-type protein.
 
  
 0.884
PP_2683
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.881
PP_2126
DNA-binding response regulator, LuxR family.
 
 
 0.872
PP_3412
DNA-binding response regulator, LuxR family.
 
 
 0.861
uvrY
Two-componenent system BarA/UvrY - regulatory subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
 
 
 0.858
bvgA
Putative Virulence factors positive transcription regulator BvgA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.856
evgA
DNA-binding response regulator in two-component regulatory system with EvgS; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.854
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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