Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pqqD-IICoenzyme PQQ synthesis protein D; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway. (90 aa)    
Predicted Functional Partners:
pqqC
Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.975
pqqB
Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.973
PP_2683
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
  
 0.934
pqqE
Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.916
yiaY
Fe-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Central intermediary metabolism.
  
  
 0.898
qedH-I
Quinoprotein ethanol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism.
 
  
 0.835
qedH-II
Quinoprotein ethanol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism.
 
  
 0.812
PP_5635
Homologs of previously reported genes of unknown function; Unknown function.
      
 0.702
aldB-II
Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family.
  
  
 0.687
PP_2684
Homologs of previously reported genes of unknown function.
      
 0.651
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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