Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
metR-IIDNA-binding transcriptional regulator, homocysteine-binding; Function of homologous gene experimentally demonstrated in an other organism; regulator; Aminoacidbiosynthesis : Aspartate family; Belongs to the LysR transcriptional regulatory family. (309 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase.
 
  
 0.690
PP_4637
5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase family protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
 
   
 0.628
PP_2699
Homologs of previously reported genes of unknown function.
 
     0.544
PP_2697
Putative oxidoreductase containing a flavin reductase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
       0.529
PP_4464
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.516
PP_2695
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
    0.439
PP_2210
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.420
PP_2701
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
    
0.410
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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