STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsHArsH protein. (233 aa)    
Predicted Functional Partners:
arsR-II
Arsenic resistance transcriptional regulator; Binds arsenite and regulates the expression of arsenic efflux pumps. In vitro, also binds antimony and bismuth, but not arsenate.
  
  
 0.880
arsB-II
Arsenite/antimonite transporter; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.
  
  
 0.858
PP_4825
Membrane protein, MarC family.
      
 0.834
PP_2716
Arsenate reductase; Function of strongly homologous gene; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.807
PP_0670
Transporter, bile acid/Na+ symporter family.
     
 0.796
chrR
Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...]
   
  
 0.741
arsR-I
Arsenic resistance transcriptional regulator; Binds arsenite and regulates the expression of arsenic efflux pumps. In vitro, also binds antimony and bismuth, but not arsenate.
     
 0.690
PP_1924
Putative Phosphinothricin N-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.658
czcC
Metal RND efflux outer membrane protein, CzcC family; Function experimentally demonstrated in the studied genus; factor; Biologicalprocesses : Excrete.
   
  
 0.649
cusB
Probable copper RND efflux membrane fusion protein, CzcB family; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Excrete; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.646
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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