Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsB-IIArsenite/antimonite transporter; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family. (427 aa)    
Predicted Functional Partners:
arsR-II
Arsenic resistance transcriptional regulator; Binds arsenite and regulates the expression of arsenic efflux pumps. In vitro, also binds antimony and bismuth, but not arsenate.
  
 0.887
PP_2716
Arsenate reductase; Function of strongly homologous gene; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.861
arsH
ArsH protein.
  
  
 0.848
PP_1927
Putative Arsenical resistance protein ArsH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.802
arsR-I
Arsenic resistance transcriptional regulator; Binds arsenite and regulates the expression of arsenic efflux pumps. In vitro, also binds antimony and bismuth, but not arsenate.
  
 0.588
cusF
Probable exported copper efflux protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Biologicalprocesses : Excrete.
      
 0.503
cusA
Probable copper efflux transporter, CzcA family; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Excrete; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.442
cusB
Probable copper RND efflux membrane fusion protein, CzcB family; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Excrete; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.436
PP_2719
Homologs of previously reported genes of unknown function.
       0.423
yfgD
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Cellularprocesses : Detoxification.
     
 0.401
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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