STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2771Sigma-54 dependent transcriptional regulator. (367 aa)    
Predicted Functional Partners:
PP_2772
Putative Monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.797
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
   
 0.792
PP_4959
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
  
 
 0.624
PP_2773
Homologs of previously reported genes of unknown function.
  
    0.606
ssuA
Aliphatic sulfonate ABC transporter - periplasmic binding protein / transport of isethionate; Function of homologous gene experimentally demonstrated in an other organism; transporter; Centralintermediarymetabolism : Sulfur metabolism.
 
 
    0.568
PP_1492
Sensor histidine kinase/response regulator.
  
 
 0.525
PP_4988
Signal transduction histidine kinase CheA/CheY-like receiver; Function of strongly homologous gene; enzyme; Signaltransduction : Two-component systems.
  
 
 0.525
glnL
Two-component system sensory histidine kinase/phosphatase GlnL/GlnG; Function of homologous gene experimentally demonstrated in an other organism; receptor; Centralintermediarymetabolism : Nitrogen metabolism.
 
 0.500
PP_4342
Flagellar synthesis regulator, putative ATPase; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 
 0.483
PP_3413
Sensor histidine kinase/response regulator.
  
 
 0.475
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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