Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_2796Homologs of previously reported genes of unknown function. (107 aa)    
Predicted Functional Partners:
actP-II
Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
 0.982
actP-III
Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
 0.923
actP-I
Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
 0.921
PP_2795
AMP-binding domain protein.
  
    0.616
PP_0354
CBS domain protein.
 
    0.595
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
    0.486
PP_2793
Acyl-CoA dehydrogenase family protein.
  
    0.449
PP_2794
Oxidoreductase, short chain dehydrogenase/reductase family.
  
    0.442
PP_2213
Putative acyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.403
prpE
propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
  
  
 0.403
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (18%) [HD]