Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ethAFAD-containing monooxygenase EthA; Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor. Preferentially converts short-chain aliphatic ketones like 2-decanone, 3-decanone and 4-decanone. Some acyclic ketones are converted not only to the alkylacetates, but also methyl- and ethylesters are obtained, indicating insertion of oxygen on both sides of the keto group; Belongs to the FAD-binding monooxygenase family. (508 aa)    
Predicted Functional Partners:
PP_2804
Hydrolase, alpha/beta fold family.
 
 0.971
PP_2807
Homologs of previously reported genes of unknown function.
 
   
 0.949
PP_3494
Homologs of previously reported genes of unknown function.
   
  
 0.854
PP_0710
Homologs of previously reported genes of unknown function; Unknown function.
      
 0.850
PP_4524
Putative Sodium-solute symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.819
xenB
Xenobiotic reductase B.
      
 0.818
uacT
Uric acid permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins.
     
 0.765
PP_0525
TonB-dependent receptor, B12 family.
      
 0.741
PP_0088
Putative alkanal monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.713
PP_1689
Putative Long-chain fatty acid transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.703
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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