STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mexCMultidrug efflux RND membrane fusion protein MexC; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (378 aa)    
Predicted Functional Partners:
oprJ
Outer membrane protein OprJ.
 
 
 0.996
mexD
Multidrug efflux RND transporter MexD.
 
 0.993
mexB
Multidrug resistance protein MexB.
 
 0.967
mexF
Multidrug efflux RND transporter MexF.
 
 
 0.963
ttgB
Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.953
ttgC
Probable efflux pump outer membrane protein TtgC; Probable outer membrane component of the TtgABC efflux pump with unknown specificity; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.910
oprN
Multidrug efflux RND outer membrane protein OprN.
 
 
 0.882
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.845
nfxB
HTH-type transcriptional regulator nfxB.
  
  
 0.838
ompQ
Outer membrane pyoverdine efflux protein; Function of strongly homologous gene; transporter; Transport and binding proteins.
 
 
 0.812
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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