mexT protein (Pseudomonas putida KT2440) - STRING interaction network

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mexT

Transcriptional regulator MexT; Belongs to the LysR transcriptional regulatory family. (304 aa)

Predicted Functional Partners:

oprN

0.953

PP_2827

0.917

oprJ

0.861

nfxB

0.849

ampD

0.814

mexF

0.794

oprD

0.766

mexB

0.762

parC

0.709

gyrA

0.704

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_2827	mexF	PP_2827	PP_3426	Alcohol dehydrogenase, zinc-containing.	Multidrug efflux RND transporter MexF.	0.819
PP_2827	mexT	PP_2827	PP_2826	Alcohol dehydrogenase, zinc-containing.	Transcriptional regulator MexT; Belongs to the LysR transcriptional regulatory family.	0.917
ampD	gyrA	PP_0789	PP_1767	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.782
ampD	mexB	PP_0789	PP_3456	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	Multidrug resistance protein MexB.	0.645
ampD	mexF	PP_0789	PP_3426	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	Multidrug efflux RND transporter MexF.	0.428
ampD	mexT	PP_0789	PP_2826	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	Transcriptional regulator MexT; Belongs to the LysR transcriptional regulatory family.	0.814
ampD	nfxB	PP_0789	PP_2820	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	HTH-type transcriptional regulator nfxB.	0.768
ampD	oprD	PP_0789	PP_1206	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	Basic-amino-acid specific porin OprD; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Porins.	0.656
ampD	oprJ	PP_0789	PP_2819	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	Outer membrane protein OprJ.	0.566
ampD	oprN	PP_0789	PP_3427	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	Multidrug efflux RND outer membrane protein OprN.	0.423
ampD	parC	PP_0789	PP_4912	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.	0.796
gyrA	ampD	PP_1767	PP_0789	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	0.782
gyrA	mexB	PP_1767	PP_3456	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Multidrug resistance protein MexB.	0.425
gyrA	mexT	PP_1767	PP_2826	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Transcriptional regulator MexT; Belongs to the LysR transcriptional regulatory family.	0.704
gyrA	nfxB	PP_1767	PP_2820	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	HTH-type transcriptional regulator nfxB.	0.672
gyrA	oprD	PP_1767	PP_1206	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Basic-amino-acid specific porin OprD; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Porins.	0.741
gyrA	oprJ	PP_1767	PP_2819	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Outer membrane protein OprJ.	0.715
gyrA	oprN	PP_1767	PP_3427	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	Multidrug efflux RND outer membrane protein OprN.	0.666
gyrA	parC	PP_1767	PP_4912	DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.	0.808
mexB	ampD	PP_3456	PP_0789	Multidrug resistance protein MexB.	N-acetyl-anhydromuramyl-L-alanine-amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatory functions.	0.645