Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fucDL-fuconate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Pentose phosphate pathway; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (411 aa)    
Predicted Functional Partners:
glcD
Glycolate oxidase, putative FAD-linked subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
     
 0.867
gnl
Gluconolactonase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
 
   
 0.836
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.774
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
      
 0.771
PP_2830
Major facilitator family transporter.
  
  
 0.751
alaC
Aminotransferase; Function of strongly homologous gene; enzyme; Regulatory functions.
     
 0.653
PP_3180
Smp-30/Cgr1 family protein.
 
   
 0.646
PP_2504
Putative tautomerase K2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 4-oxalocrotonate tautomerase family.
      
 0.567
PP_2836
Putative 2-keto-3-deoxyxylonate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Sugars.
 
   
 0.562
GbpR
Galactose-binding protein regulator; Function of strongly homologous gene; regulator; Belongs to the LysR transcriptional regulatory family.
       0.512
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.