STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_2889Putative Transmembrane regulator PrtR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (250 aa)    
Predicted Functional Partners:
PP_2888
Putative ECF sigma factor PrtI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.957
PP_2887
Catalase-related peroxidase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
 
    0.763
PP_2886
Putative Cytochrome b561; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.753
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
  
 0.673
PP_3006
RNA polymerase sigma-70 factor, ECF subfamily.
 
 
 0.563
PP_0994
Putative RNA polymerase sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.551
PP_2192
Putative RNA polymerase sigma-70 factor, ECF subfamily/transmembrane sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sigma-70 factor family.
  
 
 0.522
PP_2663
Homologs of previously reported genes of unknown function.
   
  
 0.509
PP_5319
Homologs of previously reported genes of unknown function.
 
    0.502
rpoE
RNA polymerase sigma E factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Transcription; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.492
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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