STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csiRDNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. (231 aa)    
Predicted Functional Partners:
lhgO
L-2-hydroxyglutarate oxidase; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism.
 
  
 0.927
csiD
Carbon starvation induced protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
     
 0.922
gcdR
Transcriptional activator of gcdH, LysR family; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription; Belongs to the LysR transcriptional regulatory family.
   
  
 0.836
gabD-I
Succinate-semialdehyde dehydrogenase (NADP+); Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate. Involved in L-lysine degradation.
      
 0.789
PP_3649
Transcriptional regulator, GntR family.
  
    0.760
gabT
4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate.
     
 0.749
gabD-II
Succinate-semialdehyde dehydrogenase (NADP+); Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines.
      
 0.730
PP_3738
Putative Transcriptional regulator VanR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.725
PP_4283
Transcriptional regulator, GntR family.
  
     0.717
PP_2253
Transcriptional regulator, GntR family.
  
     0.693
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.