STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lhgOL-2-hydroxyglutarate oxidase; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism. (416 aa)    
Predicted Functional Partners:
csiD
Carbon starvation induced protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 
 0.998
csiR
DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
 
  
 0.927
PP_0159
Putative CoA-transferase family III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity; Belongs to the CoA-transferase III family.
     
 0.836
gcdH
glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
   
  
 0.832
gabT
4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate.
  
  
 0.827
gabD-I
Succinate-semialdehyde dehydrogenase (NADP+); Catalyzes the conversion of 5-oxopentanoate (glutarate semialdehyde) to glutarate. Involved in L-lysine degradation.
  
  
 0.780
gcdR
Transcriptional activator of gcdH, LysR family; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription; Belongs to the LysR transcriptional regulatory family.
      
 0.737
PP_1832
Putative Oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.673
patD
Medium chain aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energymetabolism : Amino acids and amines; Belongs to the aldehyde dehydrogenase family.
  
  
 0.547
gabP-III
Gamma-aminobutyrate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids.
  
    0.485
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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